Randal R. Ketchem's Publications
Ph.D. Dissertation:
Structural Determination and Refinement of the Gramicidin A Transmembrane Channel as Studied by Solid State Nuclear Magnetic Resonance Spectroscopy
Randal R. Ketchem
Call Number QP551.K47 1995

Peer Reviewed:
  1. Immunology and Cell Biology (2008) 86, 489-496
    A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing
    Brian A. Rabinovich, Randal R. Ketchem, Martin Wolfson, Lynn Goldstein, Marylin Skelly and David Cosman

  2. Biochemistry (2008) 47, 7496-7508
    Disulfide Connectivity of Human Immunoglobulin G2 Structural Isoforms
    Theresa Martinez, Amy Guo, Martin J. Allen, Mei Han, Danielle Pace, Jay Jones, Ron Gillespie, Randal R. Ketchem, Yuling Zhang, and Alain Balland

  3. Journal of Molecular Biology (2007) 368, 1187-1201
    Biophysical Characterization of Structural Properties and Folding of Interleukin-1 Receptor Antagonist
    Ramil F. Latypov, Timothy S. Harvey, Dingjiang Liu, Pavel V. Bondarenko, Tadahiko Kohno, Roger A. Fachini II, Robert D. Rosenfeld, Randal R. Ketchem, David N. Brems, and Andrei A. Raibekas

  4. The Journal of Biological Chemistry, Vol. 277, No. 49, Issue of December 6, pp. 47619-47625, 2002
    A Single Amino Acid Difference between Human and Monkey Interleukin (IL)-1B Dictates Effective Binding to Soluble Type II IL-1 Receptor
    Dirk E. Smith, Randal R. Ketchem, Heather Moore, Zachary Anderson, Blair R. Renshaw, Della J. Friend, and John E. Sims

  5. Archives of Biochemistry and Biophysics, Vol. 392, No. 2, August 15, pp. 208-218, 2001
    Biophysical Characterization of a Soluble CD40 Ligand (CD154) Coiled-Coil Trimer: Evidence of a Reversible Acid-Denatured Molten Globule
    James E. Matsuura, Arvia E. Morris, Randal R. Ketchem, Emory H. Braswell, Ralph Klinke, Wayne R. Gombotz, and Richard L. Remmele, Jr.

  6. The Journal of Biological Chemistry, Vol. 275, No. 2, Issue of January 14, pp. 1169-1175, 2000
    Four New Members Expand the Interleukin-1 Superfamily
    Dirk E. Smith, Blair R. Renshaw, Randal R. Ketchem, Marek Kubin, Kirsten E. Garka, and John E. Sims

  7. Journal of the American Chemical Society 1999, 121, 5645-5652
    Binding-Induced Activation of DNA Alkylation by Duocarmycin SA: Insights from the Structure of an Indole Derivative-DNA Adduct
    Jason R. Schnell, Randal R. Ketchem, Dale L. Boger, and Walter J. Chazin

  8. Structure 15 February 1998, 6:223-231
    The three-dimensional structure of Ca2+-bound calcyclin: implications for Ca2+-signal transduction by S100 proteins
    Mallika Sastry, Randal R Ketchem, Orlando Crescenzi, Christoph Weber, Michael J Lubienski, Hiroyoshi Hidaka and Walter J Chazin

  9. Structure 15 December 1997, 5:1655-1669
    High-resolution polypeptide structure in a lamellar phase lipid environment from solid state NMR derived orientational constraints
    RR Ketchem, B Roux and TA Cross

  10. Journal of Biomolecular NMR, 8 (1996) 1-14
    Macromolecular structural elucidation with solid-state NMR-derived orientational constraints
    R. R. Ketchem, K. -C. Lee, S. Huo, and T. A. Cross

  11. Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, pp. 5872-5876, June 1996
    Conformational trapping in a membrane environment: A regulatory mechanism for protein activity?
    S. Arumugam, S. Pascal, C. L. North, W. Hu, K-C. Lee, M. Cotten, R. R. Ketchem, F. Xu, M. Brenneman, F. Kovacs, F. Tian, A. Wang, S. Huo, and T. A. Cross

  12. Science 261, 1457 (1993)
    High-Resolution Conformation of Gramicidin A in a Lipid Bilayer by Solid-State NMR
    R. R. Ketchem, W. Hu, T. A. Cross

Invited:

  1. Biological Membranes: a molecular perspective from computation and experiment. K. M. Merz and B. Roux, editors. Cambridge, Birkhäuser Boston: 299-322, 1996
    Computational Refinement Through Solid State NMR and Energy Constraints of a Membrane Bound Polypeptide.
    R.R. Ketchem, B. Roux and T.A. Cross

  2. Structure, 15 August 1994, 2:699-701
    Structure and dynamics from solid state NMR spectroscopy
    RR Ketchem, W Hu, F Tian and TA Cross

  3. Proceedings of the Conference on Stable Isotope Applications in Biomolecular Structure and Mechanisms, 1994
    High Resolution Polypeptide Structure in Anisotropic Environments: The Gramicidin Channel
    T.A. Cross, R.R. Ketchem, W. Hu, K.C. Lee, N.D. Lazo and S. Huo

  4. Bulletin of Magnetic Resonance 14(1-4): 96-101, 1993
    Structure and Dynamics of a Membrane Bound Polypeptide
    T.A. Cross, R.R. Ketchem, W. Hu, K.C. Lee, N.D. Lazo and C.L. North

Photography:

  1. Outdoor Photographer, Favorite Places, March, 2006
    Coal Lake, Washington
    Randal R. Ketchem

Patents Published:

  1. United States Patent Application 20070081973
    Cytokine polypeptides
    April 12, 2007
    Baum, Peter R.; Mosley, Bruce A.; Ketchem, Randal R.; Taylor, Scott L.

  2. United States Patent Application 20070072249
    Human cytokine and alpha-helix-containing polypeptides
    March 29, 2007
    Baum, Peter R.; Ketchem, Randal R.; DuBose, Robert F.; Wiley, Steven R.; Kerkof, Keith N.

  3. United States Patent Application 20060110772
    Human and murine cytokine polypeptides
    May 25, 2006
    Baum, Peter R.; Mosley, Bruce A.; Ketchem, Randal R.

  4. United States Patent Application 20050208046
    TWEAK receptor
    September 22, 2005
    Kim, Kristine M.; Wiley, Steven R.; Ketchem, Randal R.; Fanslow, William C. III

  5. United States Patent Application 20030134306
    Human and murine cytokine polypeptides
    July 17, 2003
    Baum, Peter R.; Mosley, Bruce A.; Ketchem, Randal R.

  6. United States Patent Application 20030104579
    Cytokine polypeptides
    June 5, 2003
    Baum, Peter R.; Mosley, Bruce A.; Ketchem, Randal R.; Taylor, Scott L.